What is Aclidinium? #
Aclidinium is a medication used to alleviate symptoms such as shortness of breath, coughing, or wheezing associated with chronic obstructive pulmonary disease (COPD). It’s important to note that this medication is not designed for treating sudden breathing difficulties or acute bronchospasm attacks.
Aclidinium falls under the category of bronchodilator medications known as anticholinergics. It works by relaxing the muscles in the respiratory tract, thereby widening the airways and facilitating smoother airflow to and from the lungs. However, while Aclidinium helps in managing symptoms, it does not cure COPD.
Available in the form of an inhalation liquid used with an inhaler, Aclidinium should only be used as prescribed by a healthcare professional.
How Does Aclidinium Work? #
Aclidinium works by targeting specific receptors in the respiratory tract. As an anticholinergic bronchodilator, it inhibits the action of acetylcholine, a neurotransmitter that causes muscle contractions in the airways. This relaxation of the airway muscles leads to reduced resistance and improved air passage, helping COPD patients breathe more easily.
Who Can Use Aclidinium? #
This medication is generally prescribed for adults suffering from COPD. Here are some essential considerations before using Aclidinium:
- Pregnancy and Breastfeeding: Classified under Category C, Aclidinium has shown adverse effects on animal fetuses, though controlled studies on pregnant women are lacking. The drug should only be used if the potential benefits outweigh the risks to the fetus. It is unclear whether Aclidinium is excreted in breast milk, so consultation with a doctor is necessary before use during breastfeeding.
- Allergies and Health Conditions: Patients with allergies to Aclidinium, atropine, or milk proteins should avoid this medication. It’s vital to inform your doctor about any history of prostate gland enlargement, liver or kidney disease, glaucoma, or bladder issues.
- Drug Interactions: If you are taking other medications, herbal products, or supplements, discuss with your doctor to prevent adverse drug interactions.
Dosage and Administration #
Typically, the dosage for alleviating respiratory issues due to COPD is one inhalation (322 mcg of Aclidinium) twice a day. To use an inhaler properly:
- Open the inhaler cap and ensure the mouthpiece is clean and dry.
- Exhale completely and hold your breath.
- Position the mouthpiece between your upper and lower teeth and close your lips around it.
- Press the top of the inhaler to release the medication and inhale deeply.
- Hold your breath for several seconds, then resume normal breathing.
- Clean the inhaler with a dry tissue after use.
Ensure to take Aclidinium at the same time every day. If a dose is missed, use it as soon as possible, unless it’s close to the next scheduled dose. Never double the dose to compensate for a missed one. Store the medication in a closed container at room temperature, away from direct sunlight and out of children’s reach.
Potential Drug Interactions #
When Aclidinium is used with other medications, some interactions may occur:
- Increased Side Effects: Using Aclidinium with other anticholinergic bronchodilators like tiotropium or ipratropium can amplify side effects.
- Decreased Effectiveness: The effectiveness of aripiprazole, olanzapine, or clozapine might be reduced.
- Increased Risk of Side Effects: Medications like levodopa may pose increased side effects such as tardive dyskinesia.
To avoid undesirable interactions, always consult your healthcare provider before combining Aclidinium with other drugs.
Side Effects and Risks #
Some common side effects after using Aclidinium include:
- Headaches
- Cough
- Dry mouth
- Sore throat
- Nasal congestion
- Nausea
- Diarrhea
If these symptoms persist, consult a doctor. More severe side effects require immediate medical attention, such as:
- Rapid or irregular heartbeat
- Blurred vision, eye pain, or swelling
- Difficulty urinating
- Unusual tiredness
Conclusion #
Aclidinium is a valuable medication for managing COPD symptoms, but it requires careful usage as prescribed by a doctor. Understanding its benefits, appropriate dosage, potential interactions, and side effects can significantly enhance its effectiveness and minimize risks. Always communicate openly with your healthcare provider to ensure safe and effective treatment.